Red flags
- 
Macroscopic haematuria without concurrent UTI 
- 
unexplained microscopic haematuria if aged >40yo 
- 
Recurrent or persistent UTI associated wiht haematuria if >40yo 
- 
Pelvic mass arising from urinary tract or pelvis 
- 
suspected prostatic malignancy 
Consideration for referral
- 
bladder palpable after voiding 
- 
pelvic organ prolapse 
- 
associatedfaecal incontinence 
- 
new or worsening incontinence with neurologiacl disease 
- 
symptoms of voiding difficulty 
- 
recurrent UTI 
- 
suspected or recurrent urogenital fistulae 
- 
recurrent or continued incontinence following previous continence surgery 
- 
previous pelvic cancer surgery or radiation treamtent 
Stress incontinence
leakage associated with physical activity or increased intra-abdominal pressure:
- 
coughing 
- 
sneezing 
- 
rising from chair 
- 
25-45% females aged ≥30yo 
- 
atrophy/damage to pelvic floor muscles, ligaments, fascia 
- 
associated with childbirth and menopause 
Urgency incontinence
assoiced with, or immediately after, sudden need to void
- 
volume lost = variable 
- 
complete incontience may occur 
- 
detrusor muscle overactivity 
- 
may be neurogenic 
- 
2ary to an underlying pathology or idiopathic 
- 
overactivity can result from any condition that causes loss of neuro control - 
stroke (most common) 
- 
MS 
- 
spinal cord injury 
- 
spina bifida 
 
- 
- 
2ary causes: - 
UTI 
- 
STI 
- 
interstital cystitis 
- 
atrophic vaginitis 
- 
bladder diverticula 
- 
prior pelvic radiation 
- 
surgical treatment 
 
- 
- 
idiopathic = poorly understood 
- 
occurs with aging 
- 
closely linked with overactive bladder syndrome 
Overactive bladder syndrome
idiopathic urological condition comprising urgency, frequency and often nocturia
- 
= urgency incontinence with no known cause 
- 
but may occur with no incontinence 
- 
frequency generally ≥ 8/day 
- 
loss of neurological control of detrusor muscle activity = thought to contribute 
mixed incontinence
combination of stress and urgency
- 
1/3 of women 
- 
more common with age as multiple diseases begin to occur 
- 
managmenet focuses on dominant but all causes considered/addressed 
Overflow
obstruction at bladder neck or an impairment of detrusor contractility
- 
leakage occurs from an over-filled bladder 
- 
often without urgency 
- 
more commonly seen in men 
- 
caused by - 
urethral obstruction 
- 
prlapse of pelvic organs 
- 
neruological damage 
- 
conditions that reduce sensation in bladder - 
stroke 
- 
MS 
- 
DM 
 
- 
 
- 
Other causes:
- 
functional incontinence 
- 
post void dribbling - urine remaining in urethra
 
- 
urogenital fistula - passage opens between bladder/urethra and vagina
 
Medications:
- 
Sympathomimetics - 
tightening of urinary sphincter - 
urinary retention 
- 
overflow incontincence 
 
- 
 
- 
- 
Alpha blockers - 
relaxes urinery sphincter and urethra 
- 
potentially causing stress incontinence 
 
- 
- 
ACEi - cause cough
 
- 
TCA - 
Anticholinergic effect interfere with bladder contraction 
- 
cause constipation - leading to urinary retention and overflow incontinence
 
 
- 
- 
Antihistamine - anticholinergic effect
 
- 
Antipsychotics - 
anticholinergic effect 
- 
also decrease phsyical mobility - abrupt urgency
 
 
- 
- 
CCB - 
interfere with blaadder contraction 
- 
worsen constipation 
 
- 
- 
Diuretics - increase urine production
 
- 
iron - constipation
 
- 
Opiods - 
interfere with bladder contraction 
- 
worsen constipation 
 
- 
- 
Sedatives - slow mobility and cause urgency incontinence
 
History:
- 
frequency 
- 
frequency of leakage 
- 
triggers 
- 
pads/protective devices 
- 
diet and fluid intake - including cafferine adn etoh
 
- 
lower urinary tract symptoms 
- 
other genitourinary tract symptoms 
- 
constipation and faecal incontinence 
- 
sexual function 
- 
past history of: - 
bladder surgery 
- 
hysterectomy 
- 
childbirth 
- 
previous uti 
- 
previous sti 
 
- 
- 
medicine use 
- 
smoking - associated with bladder overactivity
 
Examination
- 
assessment of patient’s general health staus 
- 
consideration of presence of systemic conditions 
- 
abdomina l examination 
- 
cough stress test - 
lie flat on back and cough 
- 
external urethral meatus for leakage during first cough 
 
- 
- 
pelvic examination 
Investigations
- 
dipstick - 
haematuria 
- 
glycosuria 
- 
signs of infection 
 
- 
- 
bladder diary - 
cover 3/y 
- 
document - 
fluids - 
amount 
- 
types 
 
- 
- 
frequency void 
- 
episodes of urgency, incontinence, pad/clothing change 
 
- 
- 
noraml amount = 200-400mL 
- 
normal freq - 
2-8time/daily 
- 
one/night 
 
- 
 
- 
- 
post void residual bladder volume - 
significant voiding symptoms 
- 
recurrent uti 
- 
symptomatic pelvic organ prolapse 
- 
bladder distension 
 
- 
- 
Urodynamic testing - 
measures - how well bladder and urethra store/release urine
 
 
- 
Pelvic organ prolapse
- 
frequent cause 
- 
pelvic floor damage in childbirth 
Anterior
- 
front wall of vagina herniated inward - usually caused by bladder nad/or urethra shifting position
 
- 
cystocoele 
- 
urethrocoele 
- 
cystourethrocele 
Posterior
- 
weakening of musculatrue and connective tissue or damage to rectovaginal septum 
- 
rectum herniate into vagina 
- 
rectocoele 
- 
enterocoele 
Apical
- 
tissue supporting uterus weakens 
- 
uterus slips downwards 
Vaginal vault prolapse
- roof of vagina collapses
Managment
General advice
- 
weight loss for any with BMI ≥30 
- 
avoid excessive fluid intake/drinking late at night 
- 
decrease caffeine and etoh 
- 
avoid constipation 
- 
stop smoking 
- 
increase phsyical activity 
Stress incontinence
- 
pelvic floor exercises - 
more likley to report cure or imporvement 
- 
3/12 
- 
individualised 
 
- 
- 
surgical - 
mid-urethral slings 
- 
intramural urethral bulking agents 
 
- 
- 
pharmacological - 
duloxetine 
- 
not subs 
- 
second-line to surgical treatmnet 
 
- 
Pelvic floor exercises
- 
strengthen muscules under uterus, bladder, bowels 
- 
tensing, holding and then relaxing muscles 
- 
3x8 od 
- 
contraction held \~10sec 
Urgency/overactive
- treat cause and train bladder
bladder training
- 
more aware of voiding and incontinence patters 
- 
learn to contorl 
- 
sceduled times are set for voiding 
- 
times between voiding gradually increased 
- 
if urgency occurs - 
‘hold on’ for short time - 10min 
- 
squeezing, holding pelvic floor 
- 
distraction 
- 
squeezing fists tightly or pushing ball of food hard onto floor 
 
- 
pharmacological
- 
oxybutyinin - 
5mg od gradually increase to 5mg tds 
- 
max = 4x daily 
- 
elderly 2.5mg 
- 
anticholinergic 
- 
reduce symptoms of urgency 
- 
increase bladder capacity 
- 
main side effect = dry mouth 
 
- 
Pelvic floor first app
https://itunes.apple.com/au/app/pelvic-floor-first/id757727900?mt=8
-