Introduction:

  • most frequently diagnosed

Transmission:

  • contact with genital secretions

  • results in infection:

    • endocervix

    • urethra

    • rectum

    • occasionaly pharynx and eye

  • accurate results obtained 1-2 weeks after potential exposure

  • incubation peiord 7-21d

  • Swabs taken too soon : false neg

  • Vertical transmission may cause conjunctivits/ophthalmia in new born

  • within 3w delivery

Symptoms:

  • asymptomatic \~70% of people

  • Men:

    • urethra discahrge

    • urethral irritation

    • dysuria

    • testicular pain/swelling

  • Females:

    • vaginal discharge

    • lower abdominal pain

    • dyspareunia

    • dysuria

    • irregular PV bleeding

    • should be considered with sterile pyuria

    • + breakthorugh bleeding

Testing:

  • all sexually active F \<25yo

    • if never been testing

    • annually

      • ≥ 2 partners last 12 mo

      • recent partner change

  • M:

    • \<25

    • ≥2 partners

    • co-infection

  • STI in past 12 mo

  • partner has STI

  • increased risk of complciation of STI

    • TOP, IUD

Lymphogranuloma vernerum

  • painless genital ulcers

    • sometimes grouping with herpetiform appearance
  • susbeqent painful chronic granulomatous inguinal lymphadenopahty

    • + anorectal disease and + chlamydia and not responding: Consider LGV

First line:

  • azithromycin 1g stat

    • safe for use in pregnant (B1)

    • better efficacy than alternatives

  • (or if not pregnant)

    • doxycyline 100mg bd for 7/7
  • repeat sexual health check in 3/12 as reinfection common

  • test of cure uncessary

    • except women treated during pregnancy or if non-standard treatment used

      • 5 weeks after

Bpac