Introduction:
- most frequently diagnosed
Transmission:
- 
contact with genital secretions 
- 
results in infection: - 
endocervix 
- 
urethra 
- 
rectum 
- 
occasionaly pharynx and eye 
 
- 
- 
accurate results obtained 1-2 weeks after potential exposure 
- 
incubation peiord 7-21d 
- 
Swabs taken too soon : false neg 
- 
Vertical transmission may cause conjunctivits/ophthalmia in new born 
- 
within 3w delivery 
Symptoms:
- 
asymptomatic \~70% of people 
- 
Men: - 
urethra discahrge 
- 
urethral irritation 
- 
dysuria 
- 
testicular pain/swelling 
 
- 
- 
Females: - 
vaginal discharge 
- 
lower abdominal pain 
- 
dyspareunia 
- 
dysuria 
- 
irregular PV bleeding 
- 
should be considered with sterile pyuria 
- 
+ breakthorugh bleeding 
 
- 
Testing:
- 
all sexually active F \<25yo - 
if never been testing 
- 
annually - 
≥ 2 partners last 12 mo 
- 
recent partner change 
 
- 
 
- 
- 
M: - 
\<25 
- 
≥2 partners 
- 
co-infection 
 
- 
- 
STI in past 12 mo 
- 
partner has STI 
- 
increased risk of complciation of STI - TOP, IUD
 
Lymphogranuloma vernerum
- 
painless genital ulcers - sometimes grouping with herpetiform appearance
 
- 
susbeqent painful chronic granulomatous inguinal lymphadenopahty - + anorectal disease and + chlamydia and not responding: Consider LGV
 
First line:
- 
azithromycin 1g stat - 
safe for use in pregnant (B1) 
- 
better efficacy than alternatives 
 
- 
- 
(or if not pregnant) - doxycyline 100mg bd for 7/7
 
- 
repeat sexual health check in 3/12 as reinfection common 
- 
test of cure uncessary - 
except women treated during pregnancy or if non-standard treatment used - 5 weeks after
 
 
- 
Bpac