Mode of transmisison: droplets

Incubation: asymptomatic nasopharyngeal carriage - common. incubation 1-3d

Vaccines:  conjugate

• PCV13

• PPV23 = polysaccharide

Schedule: 6wk, 3mo, 5mo, 15mo

efficacy: reduction in pneumococcal disease anad carriage in vaccinated populations

precaution; increase in fever and febrile convusions with concomitatnt PCV13 and influenza

Herd: reduction in pnumococcal disease in other agegroups

• S.pneumoniae

  • gram+ diplococcus

-

Clinical features

• invasive pneumococcal disease = severe end

  • endocarditis

  • deep infection in sites - joints, peritoneal

• local mucosal or non-invasive = common

  • AOM

  • sinusitis

  • pneumonia