Acute/subacute

• Arthralgia + rash +/- abdo pain

  • Henoch-Schonlein purpura

• Resp symptoms + vomiting + mental changes (seizure/coma)

  • Reye syndrome

• Pallor + drowsineess + fever

  • Meningitis

• Mailaise + fever + polyarthritis (rash, chorea)

  • Rheumatic fever

• \<3mo - male - wekaness + weight loss + vomiting

  • Pyloric stenosis

• neonate

  • vomiitng after first feeds, drooling, abdominal distension

    • oesophageal/duodenal atresia

• malaise, pallor, bone pain

  • acute leukaemia (lymphocytic)

• during gastro

  • malaise, diarrhoea, severe abdominal pain

    • Haemolytic uraemic syndrome

Developmental delay

• large ears + long narrow face + large genitals

  • fragile X syndrome

• small extremeties + narrow forehead + eating disorder

  • prader-willi syndrome

• elfin face, low set ears, cardiac murmur

  • williams syndrome

• short, webbed neck, pigmented naevi, caridacd disprder

  • turner 

• short , webbed neck, facial disproportion, caridac

  • noonan