Optic tract:
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Macula - central scotoma
 
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Anterior to optic chiasm - uniocular visual loss
 
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within the optic chism - bitemporal hemianopia
 
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posterior to optic chiasm - 
Optic tract 
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Lateral geniculate body 
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optic radiation 
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occipital cortex - 
homonymous hemianopia - 
most common cause = - 
elderly = stroke - CT = best investigation
 
 
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retinal vein occlusion
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branch vs. central 
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images 
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sudden loss of vision 
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scattered retinal haemorrhages and tortuous retinal veins - in region of occluded vein
 
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associated with hypertension 
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refer within 2 weeks 
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usually has a benign course 
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improve spont. within 2 months 
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consider laser if not improved within 3mo 
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rare causes; - 
rheumatological - 
behcet’s syndrome 
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antiphospholipid syndrome 
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protein c deficiency 
 
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inflammatory - 
sarcoidosis 
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Wegener’s granulomatosis 
 
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Exudative age related macular degeneration
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subretinal haemorrhages 
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drusen deposits - 
tiny yellow/white accumulations of extracellular material 
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noraml >40yo to have a few drusen deposits 
 
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Central retinal artery occlusion
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diffuse pallor - retinal ischaemia
 
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occlusion usually related to embolus - 
carotid arteirs or from ehart valves 
 
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fovea appears red - 
this part of retina is thin 
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intact choroidal circulation shines through fovea - “cherry red spot”
 
 
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refer within 24hours of symptoms - 
possible to prevent permanent ischaemica of retina by dislodging the embolus 
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then to stroke clinic - 
doppler 
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echocardiogram 
 
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GCA may also present with retinal artery occlusion 
retinal artery detachemnt
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inner sensory retina detaches from underlying pigmented epithelium 
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symptoms - 
floaters 
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flashers 
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Loss of vision 
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also shadow or curtain 
 
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tear or hole - secondary to posterior vitreous detachment or an ocular trauma
 
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associated with - 
congenital malformations 
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trauma 
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vascular disease 
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choroidal tumours 
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high myopia 
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vitrous disease/degeneration 
 
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Optic nuritis
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inflammation of optic nerve may be idiopathic 
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comonly associatedwith multiple sclerosis - 
risk of developing MS after episode of isolated optic neuritis = 30% at 5yrs 
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15-20% with MS present with ON 
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38-58% have ON at some point in MS course 
 
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refer opthalmologist within 1wk 
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intravenous steroids - reduce recurrence of disease
 
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oral prednisolone ineffective 
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neuromyelitis optica - iv steroid indicated
 
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impaired colour vision - red
 
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pain on eye movement 
posterior vitreous attachment
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vitreous gel that fills middle of eye - contracts and separates from retina
 
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liquefaction of vitrous jelly 
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normally occurs as people get older 
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floaters and flashers 
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can lead to retirnal tear 
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?associated with loss of vision 
Giant cell arteritis
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diagnosis can be difficult 
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28% will have skip lesions 
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American College of Rheumatology’s 1990 classification - 
=≥3 = sens 94% and 91% spec - 
>50yo 
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localised headache of new onset 
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ESR ≥ 50mm in first hour 
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tenderness in palpation over temporal artery 
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abnormal temporal artery biopsy - 
granulomatous infiltration 
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disruption of internal elastic lamina 
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proliferation of intima 
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occulsion of the lumen 
 
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ask about: - 
headahce 
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weight loss 
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shoulder pain 
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jaw claudicaiton 
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recent episodes of transient loss of vision 
 
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consider USS